GYNECOMASTIA CAUSES

Gynexin The following medical conditions are some of the possible causes of Gynecomastia. There are likely to be other possible causes.

  • Klinefelter syndrome
  • Seminiferous tubule dysgenesis
  • Testicular failure
  • Androgen-insensitivity syndrome
  • Androgen receptor defects
  • Biosynthetic defects in testosterone production
  • Feminizing adrenocortical tumors
  • Isolated Leutenizing hormone deficiency
  • Testicular germ cell tumor
  • Leydig cell tumor
  • Sertoli cell tumor
  • Pseudogynecomastia
  • Obesity – may cause similar enlarged appearance.
  • Reifenstein syndrome
  • Kallmann syndrome
  • Liver cirrhosis
  • Puberty – all adolescent males experience some male breast enlargment; it is often temporary.
  • Antiandrogens (flutamide, finasteride, ketoconazole)
  • Gastrointestinal agents (cimetidine, ranitidine)
  • Digoxin
  • Calcium channel blockers (verapamil, nifedipine)
  • Marijuana
  • Heroin
  • Methadone
  • Amphetamines
  • Androgens
  • Anabolic steroids
  • Estrogens
  • Phenothiazines
  • Diazepam
  • Tricyclic antidepressants
  • Hyperthyroidism
  • Klinefelter’s syndrome
  • Isoniazid
  • Spirionolactone
  • Cimetidine
  • Omeprazole
  • Oestrogen
  • Methyldopa
  • Physiological
  • Testicular tumours
  • Adrenal carcinoma
  • Breast cancer
  • Hepatic carcinoma
  • Hypothyroidism
  • Pituitary tumor
  • Reifenstein’s syndrome
  • Testicular cancer
  • Hemodialysis
  • Major surgery
  • Testicular irradiation
  • Estrogens to treat prostate cancer
  • Ethylstilbestrol
  • Estramustine
  • Chlorotrianisene
  • Phenothiazine
  • Antihypertensives
  • Hepatoma
  • Hypogonadism
  • Aging – more common in older men as male hormones reduce.
  • Neurofibroma
  • Lung cancer
  • Dermoid cyst
  • Liver disorders
  • Lipoma
  • Liver disease
  • Estrogen-producing tumors
  • Certain tumors
  • Feminization
  • Chronic kidney failure
  • Adrenal tumor – if it secretes estrogen
  • Hematoma
  • Lymphamgioma
  • Ectopic hCG tumor
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